Yeah!! One of the biggest strengths of Homestuck’s cast is, imo, their degree of flexibility. I wouldn’t really want to shortchange that, because it lets characters function as sort of quantum rep for different groups–like Gay vs. Bi Rose, for example–but without changing their fundamental character dynamics and relationships.
IE: You can read Rose as gay or bi, but she’s still with Kanaya in the end so it doesn’t matter much outside of how you personally relate to her. I think it’s cool that both gay and bi girls have that close reading available to them in that way, if that makes sense? Ditto Jake.